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UCM-05194

🥰Excellent
Catalog No. T69647Cas No. 2411412-36-5
Alias UCM05194, UCM 05194

UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.

UCM-05194

UCM-05194

🥰Excellent
Catalog No. T69647Alias UCM05194, UCM 05194Cas No. 2411412-36-5
UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$333-In Stock
5 mg$790-In Stock
10 mg$1,120-In Stock
25 mg$1,670-In Stock
50 mg$2,180-In Stock
100 mg$2,930-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Product Introduction

Bioactivity
Description
UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.
In vitro
METHODS: B103 neuroblastoma cells overexpressing LPA1 receptors were seeded (2.5·105 cells) into the upper chamber of a transwell and vehicle (0.1% fatty acid-free bovine serum albumin), LPA 1 μM, or UCM-05194 were added to the lower chamber. After allowing cells to migrate for 5 h, migrated cells were stained with 0.1% crystal violet solution and counted.
RESULTS: UCM-05194 induced neurite retraction and UCM-05194 induced cell migration in B103 cells overexpressing LPA1 in the transwell chamber assay. [1]
SynonymsUCM05194, UCM 05194
Chemical Properties
Molecular Weight465.32
FormulaC19H30BrO6P
Cas No.2411412-36-5
SmilesC(CCCCCCCCC(O[C@@H](COP(=O)(O)O)CBr)=O)C1=CC=CC=C1
ColorYellow
AppearanceOil
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 16.67 mg/mL (35.82 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1491 mL10.7453 mL21.4906 mL107.4529 mL
5 mM0.4298 mL2.1491 mL4.2981 mL21.4906 mL
10 mM0.2149 mL1.0745 mL2.1491 mL10.7453 mL
20 mM0.1075 mL0.5373 mL1.0745 mL5.3726 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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