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UCM-05194

Name: UCM-05194
Brand: TargetMol
SKU: T69647
Price: 333 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T69647Cas No. 2411412-36-5

Alias UCM05194, UCM 05194

UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.

UCM-05194

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Catalog No. T69647Alias UCM05194, UCM 05194Cas No. 2411412-36-5

UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$333	-	In Stock
5 mg	$790	-	In Stock
10 mg	$1,120	-	In Stock
25 mg	$1,670	-	In Stock
50 mg	$2,180	-	In Stock
100 mg	$2,930	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Oil

Color:Yellow

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Product Introduction

Bioactivity

Description	UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.
In vitro	METHODS: B103 neuroblastoma cells overexpressing LPA1 receptors were seeded (2.5·105 cells) into the upper chamber of a transwell and vehicle (0.1% fatty acid-free bovine serum albumin), LPA 1 μM, or UCM-05194 were added to the lower chamber. After allowing cells to migrate for 5 h, migrated cells were stained with 0.1% crystal violet solution and counted. RESULTS: UCM-05194 induced neurite retraction and UCM-05194 induced cell migration in B103 cells overexpressing LPA1 in the transwell chamber assay. [1]
Synonyms	UCM05194, UCM 05194

Chemical Properties

Molecular Weight	465.32
Formula	C₁₉H₃₀BrO₆P
Cas No.	2411412-36-5
Smiles	C(CCCCCCCCC(O[C@@H](COP(=O)(O)O)CBr)=O)C1=CC=CC=C1

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 16.67 mg/mL (35.82 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1491 mL	10.7453 mL	21.4906 mL	107.4529 mL
5 mM	0.4298 mL	2.1491 mL	4.2981 mL	21.4906 mL
10 mM	0.2149 mL	1.0745 mL	2.1491 mL	10.7453 mL
20 mM	0.1075 mL	0.5373 mL	1.0745 mL	5.3726 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc