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SKF 10810

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Catalog No. T206064Cas No. 22196-65-2

SKF 10810 is a GABAA receptor antagonist with an EC50 of 4.3 μM. It exhibits antidepressant effects by blocking the inhibitory action of the GABAergic system on the brain's reward pathways. SKF 10810 is utilized in research related to neurological disorders.

SKF 10810

SKF 10810

😃Good
Catalog No. T206064Cas No. 22196-65-2
SKF 10810 is a GABAA receptor antagonist with an EC50 of 4.3 μM. It exhibits antidepressant effects by blocking the inhibitory action of the GABAergic system on the brain's reward pathways. SKF 10810 is utilized in research related to neurological disorders.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
SKF 10810 is a GABAA receptor antagonist with an EC50 of 4.3 μM. It exhibits antidepressant effects by blocking the inhibitory action of the GABAergic system on the brain's reward pathways. SKF 10810 is utilized in research related to neurological disorders.
Chemical Properties
Molecular Weight335.363
FormulaC19H20F3NO
Cas No.22196-65-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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