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Tesidolumab (Synonyms: LFG316)

Catalog No. T76831 Copy Product Info
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Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis.

Tesidolumab

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Catalog No. T76831
Synonyms LFG316

Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis.

Tesidolumab
Cas No. 1531594-08-7
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$198In StockIn Stock
5 mg$496In StockIn Stock
10 mg$828-In Stock
25 mg$1,230-In Stock
50 mg$1,650-In Stock
100 mg$2,230-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.72% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis.
In vitro
Tesidolumab (LFG316) has a half-life of approximately 9 days in humans and binds to a unique epitope distant from Arg 885, differentiating it from eculizumab and ravulizumab in its binding site[1].
SynonymsLFG316
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetComplement C5
Chemical Properties
Molecular Weight144.16 kDa
Cas No.1531594-08-7
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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