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ARV-393 is a BCL6 PROTAC degrader with DC50 and GI50 values of <1 nM in both DLBCL and BL cell lines. ARV-393 inhibits tumor volume in multiple tumor xenograft models.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $268 | In Stock | |
5 mg | $668 | In Stock | |
10 mg | $1,058 | In Stock | |
25 mg | $2,100 | In Stock |
Description | ARV-393 is a BCL6 PROTAC degrader with DC50 and GI50 values of <1 nM in both DLBCL and BL cell lines. ARV-393 inhibits tumor volume in multiple tumor xenograft models. |
Molecular Weight | 898.43 |
Formula | C46H53O7ClFN9 |
Cas No. | 2851885-95-3 |
Smiles | FC1=C2C(C(=O)N(C2)C3C(=O)NC(=O)CC3)=CC=C1C4CCN(CC4)[C@@H]5C[C@@H](OC6CCN(CC6)C=7N=C(NC=8C=C9C(=CC8)N(C(C)C)C(=O)C(OCC(NC)=O)=C9)C(Cl)=CN7)C5 |
Relative Density. | 1.45 g/cm3 at 20℃ (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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