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Anti-Complement Factor B Antibody
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Catalog No. T9901A-1417 Copy Product Info
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Anti-Complement Factor B Antibody is a highly specialized humanized monoclonal antibody target and neutralize complement factor B, inhibition of the alternative complement pathway by disrupting the enzymatic assembly of the C3 convertase complex across various immunological experimental models.
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| Description | Anti-Complement Factor B Antibody is a highly specialized humanized monoclonal antibody target and neutralize complement factor B, inhibition of the alternative complement pathway by disrupting the enzymatic assembly of the C3 convertase complex across various immunological experimental models. |
| In vitro | In alternative pathway hemolysis assays, Anti-Complement Factor B Antibody (13192) inhibited complement activation with an IC50 of 0.5 ug/mL [1]. |
| In vivo | In mouse models of collagen-induced arthritis, systemic administration of 2 mg Anti-Complement Factor B Antibody (13192) significantly reduced clinical scores and joint bone destruction [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | ComplementFactorB |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-Complement Factor B Antibody chemical structure | Anti-Complement Factor B Antibody in vivo | Anti-Complement Factor B Antibody in vitro
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