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Anti-Complement Factor B Antibody is a highly specialized humanized monoclonal antibody target and neutralize complement factor B, inhibition of the alternative complement pathway by disrupting the enzymatic assembly of the C3 convertase complex across various immunological experimental models.

| Description | Anti-Complement Factor B Antibody is a highly specialized humanized monoclonal antibody target and neutralize complement factor B, inhibition of the alternative complement pathway by disrupting the enzymatic assembly of the C3 convertase complex across various immunological experimental models. |
| In vitro | In alternative pathway hemolysis assays, Anti-Complement Factor B Antibody (13192) inhibited complement activation with an IC50 of 0.5 ug/mL [1]. |
| In vivo | In mouse models of collagen-induced arthritis, systemic administration of 2 mg Anti-Complement Factor B Antibody (13192) significantly reduced clinical scores and joint bone destruction [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | ComplementFactorB |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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