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Human Factor XIIa Beta

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Catalog No. TRP-00496

Human Factor XIIa Beta is an active fragment of coagulation factor XII, playing a crucial role in the intrinsic coagulation pathway and leading to clot formation. Additionally, Human Factor XIIa Beta is involved in the kallikrein-kinin system, resulting in the release of bradykinin (a vasodilator). Bradykinin stimulates the release of catecholamines and mediates its cardiovascular effects through a non-cholinergic, angiotensin-converting enzyme (ACE) regulatory mechanism.

Human Factor XIIa Beta

Human Factor XIIa Beta

😃Good
Catalog No. TRP-00496
Human Factor XIIa Beta is an active fragment of coagulation factor XII, playing a crucial role in the intrinsic coagulation pathway and leading to clot formation. Additionally, Human Factor XIIa Beta is involved in the kallikrein-kinin system, resulting in the release of bradykinin (a vasodilator). Bradykinin stimulates the release of catecholamines and mediates its cardiovascular effects through a non-cholinergic, angiotensin-converting enzyme (ACE) regulatory mechanism.
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Bioactivity
Description
Human Factor XIIa Beta is an active fragment of coagulation factor XII, playing a crucial role in the intrinsic coagulation pathway and leading to clot formation. Additionally, Human Factor XIIa Beta is involved in the kallikrein-kinin system, resulting in the release of bradykinin (a vasodilator). Bradykinin stimulates the release of catecholamines and mediates its cardiovascular effects through a non-cholinergic, angiotensin-converting enzyme (ACE) regulatory mechanism.
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Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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