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IL-1 alpha/IL-1A Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: Interleukin-1 α, Interleukin-1 Alpha, IL1F1, IL1A, IL-1 α, IL-1 Alpha, Hematopoietin-1) Copy Product Info

Synonyms: Interleukin-1 α, Interleukin-1 Alpha, IL1F1, IL1A, IL-1 α, IL-1 Alpha, Hematopoietin-1

Catalog No. TMPJ-00161 Copy Product Info
IL-1 alpha/IL-1A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is P01583.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$1297-10 days7-10 days
10 µg$2137-10 days7-10 days
20 µg$3557-10 days7-10 days
50 µg$6257-10 days7-10 days
100 µg$9637-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Human IL-1R1, No Tag immobilized on CM5 Chip can bind Biotinylated Human IL-1 alpha, His-Avi Tag with an affinity constant of 1.01 μM as determined in SPR assay (Biacore T200).
Description
IL-1 alpha/IL-1A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is P01583.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP01583
Amino AcidSer113-Ala271
ConstructionSer113-Ala271
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin< 1 EU/µg as determined by LAL test.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsInterleukin-1 α, Interleukin-1 Alpha, IL1F1, IL1A, IL-1 α, IL-1 Alpha, Hematopoietin-1
Research Background
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
Chemical Properties
Molecular Weight20.95 kDa (predicted); 25-32 kDa (due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-1 alpha/IL-1A Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | IL-1 alpha/IL-1A Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight