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Dexamethasone (Standard) is a reference standard for Dexamethasone, applicable for quantitative analysis, quality control, and biochemical experiments. Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator exhibiting anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It suppresses production of inflammatory iRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, inhibits LPS-induced macrophage inflammatory responses while inducing autophagy. It is commonly used to induce animal models of depression, muscular dystrophy, and hypertension, and shows potential in COVID-19 research.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $52 | 7-10 days | 7-10 days |
| Description | Dexamethasone (Standard) is a reference standard for Dexamethasone, applicable for quantitative analysis, quality control, and biochemical experiments. Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator exhibiting anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It suppresses production of inflammatory iRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, inhibits LPS-induced macrophage inflammatory responses while inducing autophagy. It is commonly used to induce animal models of depression, muscular dystrophy, and hypertension, and shows potential in COVID-19 research. |
| Synonyms | Prednisolone F (Standard), Hexadecadrol (Standard) |
| Molecular Weight | 392.46 |
| Formula | C22H29FO5 |
| Cas No. | 50-02-2 |
| Smiles | F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H] |
| Relative Density. | 1.32 g/cm3 |
| Storage | keep away from direct sunlight | store at -80°C |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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