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Synonyms: RAB7B, MHC


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $147 | 7-10 days | 7-10 days | |
| 20 µg | $228 | 7-10 days | 7-10 days | |
| 50 µg | $419 | 7-10 days | 7-10 days | |
| 100 µg | $665 | 7-10 days | 7-10 days | |
| 200 µg | $1,050 | 7-10 days | 7-10 days | |
| 500 µg | $1,960 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated is expressed in E. coli. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)&KLIIVGAIGV. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His-Avi |
| Accession Number | A0A140T913(HLA-A*02:01)&P61769(B2M)&KLIIVGAIGV |
| Construction | Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KLIIVGAIGV peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | RAB7B, MHC |
| Research Background | Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identified Rab protein that may downregulate TLR4 and TLR9-mediated inflammatory responses. Rab7b, believed to have similar function as Rab7, controls however vesicular trafficking from endosomes to the TGN. It is localized to late endosomes/lysosomes as well as the TGN. Rab7b interferes with enzymes delivery to lysosomes and with the retrograde Shiga toxin transport to the Golgi. |
| Molecular Weight | 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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