1.25% Avertin (Anesthesia For Mice)

1.25% Avertin (an anaesthetic for mice) is a sterile solution specifically formulated for short-acting anaesthesia in laboratory animals, particularly mice. It employs high-purity tribromoethanol as the primary active ingredient, supplemented with trace amounts of tert-amyl alcohol as a solubilising agent, and is prepared with physiological saline to achieve a standard concentration of 1.25%.
Tribromoethanol acts as a central nervous system depressant by enhancing chloride influx mediated through GABAA receptors, thereby inhibiting neuronal depolarisation and suppressing neural excitation. This mechanism rapidly induces sedation and anaesthesia. Avertin, being a fast-acting, short-duration anaesthetic, is extensively employed in acute procedures involving mice, such as surgery, cardiac puncture, tissue perfusion, and sample collection. A concentration of 1.25% is the commonly recommended dose for mice, balancing anaesthetic depth with safety.
This product is a ready-to-use formulation, sterile-filtered to ensure safety and stability. It is suitable for direct intraperitoneal anaesthesia in research animals, eliminating the need for user-dependent dissolution or filtration.