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Temocillin disodium

🥰Excellent
Catalog No. T40699Cas No. 61545-06-0
Alias Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodium

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.

Temocillin disodium
Other Forms of Temocillin disodium:
TemocillinT7437866148-78-5
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Temocillin disodium

🥰Excellent
Catalog No. T40699Alias Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodiumCas No. 61545-06-0
Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
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1 mg$30In Stock
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Product Introduction

Bioactivity
Description
Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
In vivo
The dosing regimen of Temocillin disodium is 200 mg/kg every 4 or 6 hours, which significantly reduces the bacterial counts of both strains in the kidneys, with no significant difference observed between the parental strain and its transconjugant. [2]
SynonymsTemopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodium
Chemical Properties
Molecular Weight458.42
FormulaC16H16N2Na2O7S2
Cas No.61545-06-0
SmilesCO[C@@]1(NC(=O)C(C(=O)[O-])c2ccsc2)C(=O)N2[C@@H](C(=O)[O-])C(C)(C)S[C@@H]21.[Na+].[Na+]
Relative Density.1.6g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 200 mg/mL (436.28 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.1814 mL10.9070 mL21.8141 mL109.0703 mL
5 mM0.4363 mL2.1814 mL4.3628 mL21.8141 mL
10 mM0.2181 mL1.0907 mL2.1814 mL10.9070 mL
20 mM0.1091 mL0.5454 mL1.0907 mL5.4535 mL
50 mM0.0436 mL0.2181 mL0.4363 mL2.1814 mL
100 mM0.0218 mL0.1091 mL0.2181 mL1.0907 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Temocillin disodiumTemocillinBRL-17421BRL17421BRL 17421Bacterial
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