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Temocillin disodium

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Catalog No. T40699Cas No. 61545-06-0
Alias Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodium

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.

Temocillin disodium
Other Forms of Temocillin disodium:
TemocillinT7437866148-78-5
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Temocillin disodium

🥰Excellent
Catalog No. T40699Alias Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodiumCas No. 61545-06-0
Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
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1 mg$30-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
In vivo
The dosing regimen of Temocillin disodium is 200 mg/kg every 4 or 6 hours, which significantly reduces the bacterial counts of both strains in the kidneys, with no significant difference observed between the parental strain and its transconjugant. [2]
SynonymsTemopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodium
Chemical Properties
Molecular Weight458.42
FormulaC16H16N2Na2O7S2
Cas No.61545-06-0
SmilesCO[C@@]1(NC(=O)C(C(=O)[O-])c2ccsc2)C(=O)N2[C@@H](C(=O)[O-])C(C)(C)S[C@@H]21.[Na+].[Na+]
Relative Density.1.6g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 200 mg/mL (436.28 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.1814 mL10.9070 mL21.8141 mL109.0703 mL
5 mM0.4363 mL2.1814 mL4.3628 mL21.8141 mL
10 mM0.2181 mL1.0907 mL2.1814 mL10.9070 mL
20 mM0.1091 mL0.5454 mL1.0907 mL5.4535 mL
50 mM0.0436 mL0.2181 mL0.4363 mL2.1814 mL
100 mM0.0218 mL0.1091 mL0.2181 mL1.0907 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Temocillin disodiumTemocillinBRL-17421BRL17421BRL 17421Bacterial
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