keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide that primarily interacts with and activates the CRF receptor type 2 (CRF-R2), showing a specific distribution in the central nervous system and periphery. It selectively attaches to type 2 CRF receptors, exhibiting dissociation constants (Ki values) of 13.5 nM for mouse CRF2β, 21.7 nM for rat CRF2α, and <100 nM for human CRF1, indicating a strong preference for CRF-R2 over CRF1. Furthermore, Urocortin III (human) plays a crucial role in the somatostatin-dependent negative feedback mechanism that regulates the secretion of Insulin (human).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 458.00 | |
1 mg | 35 days | $ 823.00 |
Description | Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide that primarily interacts with and activates the CRF receptor type 2 (CRF-R2), showing a specific distribution in the central nervous system and periphery. It selectively attaches to type 2 CRF receptors, exhibiting dissociation constants (Ki values) of 13.5 nM for mouse CRF2β, 21.7 nM for rat CRF2α, and >100 nM for human CRF1, indicating a strong preference for CRF-R2 over CRF1. Furthermore, Urocortin III (human) plays a crucial role in the somatostatin-dependent negative feedback mechanism that regulates the secretion of Insulin (human). |
Molecular Weight | 4137.93 |
Formula | C185H307N53O50S2 |
CAS No. | 357952-09-1 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Urocortin III (human) 357952-09-1 inhibitor inhibit