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Ziltivekimab
(Synonyms: WBP-216, WBP216, MEDI5117, MEDI 5117, EX-6018, EX6018, COR-001, COR001) Copy Product Info
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Synonyms: WBP-216, WBP216, MEDI5117, MEDI 5117, EX-6018, EX6018, COR-001, COR001
Catalog No. T9901A-074 Copy Product Info
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Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.
Cas No. 2226654-05-1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $310 | - | In Stock | |
| 5 mg | $536 | - | In Stock | |
| 10 mg | $805 | - | In Stock | |
| 25 mg | $1,665 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.9% (SDS-PAGE); 97.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Chemical Properties
Antibody Information
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| Description | Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases. |
| In vitro | Methods: Fasting venous whole blood was collected from high-risk cardiovascular patients following PCI. The samples were incubated at room temperature with 1.5 μg/mL ziltivekimab for 30 minutes, followed by stimulation with 5 μM ADP, 2 μg/mL Collagen-rP, and 10 μM TRAP-6 at room temperature for 30 minutes. Platelet activation was assessed by flow cytometric analysis of CD62P expression. Results: Following treatment with ziltivekimab, the activation response of patients’ platelets to Collagen-rP was significantly reduced; there was no significant effect on the activation responses to ADP or TRAP-6. [2] |
| Synonyms | WBP-216, WBP216, MEDI5117, MEDI 5117, EX-6018, EX6018, COR-001, COR001 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-6/IFNb2 |
| Molecular Weight | 145.39 kDa |
| Cas No. | 2226654-05-1 |
| Relative Density. | no data available |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Ziltivekimab chemical structure | Ziltivekimab in vitro | Ziltivekimab molecular weight
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