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potent

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  • Inhibitors & Agonists
    12762
    TargetMol | Inhibitors_Agonists
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    TargetMol | Inhibitors_Agonists
BMS-986242
BMS986242
T91641923844-48-7
BMS-986242 is an orally active, potent, and selective indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor, suitable for cancer research.
  • $86
In Stock
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TargetMol | Inhibitor Sale
CYM50308
T150321345858-76-5
CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more selective for S1P4-R than S1P5-R.
  • $56
In Stock
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Maytansine
NSC-153858, NSC153858, NSC 153858, Maitansine, Maitansina
T2135135846-53-8
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
  • $30
In Stock
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Olodaterol
Striverdi Respimat, BI1744
T3457868049-49-4
Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs.
  • $42
In Stock
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Olodaterol hydrochloride
BI-1744 HCl, BI 1744 hydrochloride
T5159869477-96-3
Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adrenergic receptors.
  • $56
In Stock
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SB-366791
SB366791
T6977472981-92-3
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
  • $30
In Stock
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QTY
PF-9363
CTX-3648
T91672569009-58-9
PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.
  • $67
In Stock
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GLPG2938
1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea
T91992130996-00-6
GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2.
  • $76
In Stock
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SBC-115337
T9276423148-46-3
SBC-115337 is a PCSK9 inhibitor.
  • $53
In Stock
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TargetMol | Inhibitor Sale
Emodin 6-O-β-D-glucoside
Glucoemodin
TN677434298-85-6
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.
  • $73
In Stock
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Bradykinin potentiator B
T7650530892-86-5
Bradykinin Potentiator B (also known as Bradykinin Potentiating Peptide B), derived from the venom of Agkistrodon halys blomhoffi, serves as a potent ACE inhibitor. It effectively inhibits the activity of bradykinin inhibitory peptidase [1].
  • Inquiry Price
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Bradykinin potentiator C
T7650730953-20-9
Bradykinin Potentiator C, a potent inhibitor of angiotensin-converting enzyme (ACE) with an inhibitory concentration (IC 50) of 7.1 μM for rabbit lung ACE, is regarded as a prototype for functional peptides [1].
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KCC2 potentiators-1
T2034143058906-46-7
Compound 2, known as KCC2 potentiators-1, acts as an enhancer of the potassium chloride cotransporter-2 (KCC2). It holds potential for applications in studies related to neurological disorders.
  • Inquiry Price
10-14 weeks
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aminopotentidine
T22566140873-26-3
H2 antagonist
  • $1,670
6-8 weeks
Size
QTY
Bradykinin potentiator-5
BPP-5a , BPP5a , BPP 5a
T2517330505-63-6
Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.
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OV-potentiator-28
OV potentiator 28
T28276
OV-potentiator-28 is a potentiator of cancer virotherapy. OV-potentiator-28 significantly enhances virus replication-associated luciferase expression, specifically in tumors.
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nmda receptor potentiator-1
T63003486427-18-3
NMDA receptor potentiator-1 (Compound 1368) is a subunit-selective NMDA receptor enhancer with IC50 values of 4 μM for NR2C and 5 μM for NR2D expression.
  • $1,520
6-8 weeks
Size
QTY
Potentillanoside A
T814181309589-79-4
Potentillanoside A is a natural hepatoprotective compound [1].
  • Inquiry Price
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Ruxolitinib
INCB018424, (R)-Ruxolitinib
T1829941678-49-5
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
  • $53
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TargetMol | Inhibitor Hot
Liproxstatin-1
T2376950455-15-9
Liproxstatin-1 is a potent and selective inhibitor of ferroptosis (IC50=22 nM). Liproxstatin-1 protects cells from ferroptosis induced by ferroptosis inducers (e.g., Erastin, RSL3).
  • $33
In Stock
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TargetMol | Inhibitor Hot
RMC-6236
RMC6236, RAS-IN-2, Daraxonrasib
T746982765081-21-6
RMC-6236 is an orally effective and novel triple complex RAS (ON) MULTI inhibitor, which is a potent non covalent inhibitor of multiple RAS variants in GTP binding state. RMC-6236 has anti-tumor activity and can be used in research related to RAS driven tumors. With rich experience in compound synthesis, we can provide fast customized synthesis services for this product according to your research needs.
  • $58
In Stock
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TargetMol | Inhibitor Hot
MRTX1133
T93032621928-55-8In house
MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
  • $197
In Stock
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TargetMol | Inhibitor Hot
Q-VD-OPH
Quinoline-Val-Asp-Difluorophenoxymethylketone
T02821135695-98-5
Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12. Q-VD-OPh inhibits HIV infection and can cross the blood-brain barrier.
  • $47
In Stock
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TargetMol | Inhibitor Hot
Edaravone
MCI-186
T040789-25-8
Edaravone (MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.
  • $29
In Stock
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TargetMol | Inhibitor Hot