Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 35 days | $ 150.00 | |
500 μg | 35 days | $ 648.00 | |
1 mg | 35 days | $ 1,140.00 | |
5 mg | 35 days | $ 4,770.00 |
Description | Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg. |
Synonyms | JMV3002 |
Molecular Weight | 586.68 |
Formula | C35H34N6O3 |
CAS No. | 925239-03-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
DMSO: 20 mg/mL
DMF: 30 mg/mL
Ethanol: 30 mg/mL
You can also refer to dose conversion for different animals. More
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JMV3002 925239-03-8 JMV-3002 JMV 3002 inhibitor inhibit