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(R)-ZINC-3573

Name: (R)-ZINC-3573
Brand: TargetMol
SKU: T29221
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T29221Cas No. 2089389-15-9

Alias ZINC 3573

(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.

(R)-ZINC-3573

🥰Excellent

Purity: 99.75%

Catalog No. T29221Alias ZINC 3573Cas No. 2089389-15-9

(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.

Pack Size	Price	Availability
2 mg	$39	In Stock
5 mg	$64	In Stock
10 mg	$97	In Stock
25 mg	$228	In Stock
50 mg	$343	In Stock
100 mg	$497	In Stock
1 mL x 10 mM (in DMSO)	$70	In Stock

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Batch Information

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Purity:99.75%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
Synonyms	ZINC 3573

Chemical Properties

Molecular Weight	307.39
Formula	C₁₈H₂₁N₅
Cas No.	2089389-15-9
Smiles	CN(C)[C@@H]1CCN(C1)c1cc(nc2ccnn12)-c1ccccc1
Relative Density.	1.23 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.7 mg/mL (90.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2532 mL	16.2660 mL	32.5320 mL	162.6598 mL
5 mM	0.6506 mL	3.2532 mL	6.5064 mL	32.5320 mL
10 mM	0.3253 mL	1.6266 mL	3.2532 mL	16.2660 mL
20 mM	0.1627 mL	0.8133 mL	1.6266 mL	8.1330 mL
50 mM	0.0651 mL	0.3253 mL	0.6506 mL	3.2532 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc