Shopping Cart
Remove All
Your shopping cart is currently empty
Procaspase-3 activator 1
Catalog No. T213987 Copy Product Info
🥰Excellent
Procaspase-3 activator 1 is a potent activator of procaspase-3. It directly activates procaspase-3 through zinc chelation, inducing apoptosis and inhibiting cancer cell proliferation. Procaspase-3 activator 1 is applicable in research on non-small cell lung cancer (NSCLC) and melanoma.
Procaspase-3 activator 1
Copy Product Info🥰Excellent
Catalog No. T213987
Procaspase-3 activator 1 is a potent activator of procaspase-3. It directly activates procaspase-3 through zinc chelation, inducing apoptosis and inhibiting cancer cell proliferation. Procaspase-3 activator 1 is applicable in research on non-small cell lung cancer (NSCLC) and melanoma.
Procaspase-3 activator 1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Procaspase-3 activator 1 is a potent activator of procaspase-3. It directly activates procaspase-3 through zinc chelation, inducing apoptosis and inhibiting cancer cell proliferation. Procaspase-3 activator 1 is applicable in research on non-small cell lung cancer (NSCLC) and melanoma. |
| In vitro | Procaspase-3 activator 1 (compound K-15) exhibits significant antiproliferative activity against A549 and A375 cells with IC50 values of 3.96 µM and 21.18 µM, respectively, while maintaining negligible cytotoxicity at 10 μM in BEAS-2B cells, indicating its selectivity. Additionally, Procaspase-3 activator 1 (50 μM, 0-180 minutes) directly converts precursor caspase-3 into active caspase-3, demonstrating superior activation activity compared to the positive control, PAC-1. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Citations
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Procaspase-3 activator 1 | purchase Procaspase-3 activator 1 | Procaspase-3 activator 1 cost | order Procaspase-3 activator 1 | Procaspase-3 activator 1 in vitro
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.