Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

BAY 1214784

Copy Product Info
😃Good
Catalog No. T72990Cas No. 1631164-25-4
Alias BAY-1214784, BAY1214784

BAY 1214784 is a selective and orally active human GnRH-R (Human Gonadotropin-Releasing Hormone Receptor) antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49% and can be used for the study of uterine fibroids.

BAY 1214784

BAY 1214784

Copy Product Info
😃Good
Purity: 100%
Catalog No. T72990Alias BAY-1214784, BAY1214784Cas No. 1631164-25-4
BAY 1214784 is a selective and orally active human GnRH-R (Human Gonadotropin-Releasing Hormone Receptor) antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49% and can be used for the study of uterine fibroids.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$89-In Stock
5 mg$225-In Stock
10 mg$335-In Stock
25 mg$558-In Stock
50 mg$798-In Stock
100 mg$1,080-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:100%
ee:100%
Appearance:Solid
Color:White
Contact us for more batch information

Resource Download

Product Introduction

Bioactivity
Description
BAY 1214784 is a selective and orally active human GnRH-R (Human Gonadotropin-Releasing Hormone Receptor) antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49% and can be used for the study of uterine fibroids.
SynonymsBAY-1214784, BAY1214784
Chemical Properties
Molecular Weight672.11
FormulaC29H26ClF4N3O5S2
Cas No.1631164-25-4
SmilesS(=O)(=O)(N1[C@@H](C2(C=3C1=CC=C(C(NCC4=C(Cl)C=C(C(F)(F)F)C=N4)=O)C3)CCS(=O)(=O)CC2)[C@H]5CC5)C6=CC=C(F)C=C6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (44.64 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4879 mL7.4393 mL14.8785 mL74.3926 mL
5 mM0.2976 mL1.4879 mL2.9757 mL14.8785 mL
10 mM0.1488 mL0.7439 mL1.4879 mL7.4393 mL
20 mM0.0744 mL0.3720 mL0.7439 mL3.7196 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy BAY 1214784 | purchase BAY 1214784 | BAY 1214784 cost | order BAY 1214784 | BAY 1214784 chemical structure | BAY 1214784 formula | BAY 1214784 molecular weight