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BAY 1214784

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Catalog No. T72990Cas No. 1631164-25-4
Alias BAY-1214784, BAY1214784

BAY 1214784 is a selective and orally active human GnRH-R (Human Gonadotropin-Releasing Hormone Receptor) antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49% and can be used for the study of uterine fibroids.

BAY 1214784

BAY 1214784

😃Good
Purity: 100%
Catalog No. T72990Alias BAY-1214784, BAY1214784Cas No. 1631164-25-4
BAY 1214784 is a selective and orally active human GnRH-R (Human Gonadotropin-Releasing Hormone Receptor) antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49% and can be used for the study of uterine fibroids.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$89-In Stock
5 mg$225-In Stock
10 mg$335-In Stock
25 mg$558-In Stock
50 mg$798-In Stock
100 mg$1,080-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:100%
ee:100%
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Product Introduction

Bioactivity
Description
BAY 1214784 is a selective and orally active human GnRH-R (Human Gonadotropin-Releasing Hormone Receptor) antagonist, which can effectively reduce plasma luteinizing hormone levels by up to 49% and can be used for the study of uterine fibroids.
SynonymsBAY-1214784, BAY1214784
Chemical Properties
Molecular Weight672.11
FormulaC29H26ClF4N3O5S2
Cas No.1631164-25-4
SmilesS(=O)(=O)(N1[C@@H](C2(C=3C1=CC=C(C(NCC4=C(Cl)C=C(C(F)(F)F)C=N4)=O)C3)CCS(=O)(=O)CC2)[C@H]5CC5)C6=CC=C(F)C=C6
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (44.64 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4879 mL7.4393 mL14.8785 mL74.3926 mL
5 mM0.2976 mL1.4879 mL2.9757 mL14.8785 mL
10 mM0.1488 mL0.7439 mL1.4879 mL7.4393 mL
20 mM0.0744 mL0.3720 mL0.7439 mL3.7196 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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