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Fullerene-C60
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Catalog No. T41141Cas No. 99685-96-8
Fullerene-C60 is a potent free radical scavenger with a wide range of bioactivities that can attenuate liver injury and hepatotoxicity, and improve intestinal flora structure and lipid homeostasis.
Fullerene-C60
😃Good
Catalog No. T41141Cas No. 99685-96-8
Fullerene-C60 is a potent free radical scavenger with a wide range of bioactivities that can attenuate liver injury and hepatotoxicity, and improve intestinal flora structure and lipid homeostasis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $42 | - | In Stock | |
| 25 mg | $68 | - | In Stock | |
| 50 mg | $98 | - | In Stock | |
| 100 mg | $159 | - | In Stock | |
| 500 mg | $397 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:Black
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| Description | Fullerene-C60 is a potent free radical scavenger with a wide range of bioactivities that can attenuate liver injury and hepatotoxicity, and improve intestinal flora structure and lipid homeostasis. |
| In vitro | Methods: To estimate the accumulation of Fullerene-C60 in leukemic cells and to investigate its phototoxic effects on parental and cisplatin-treated leukemic cells. A stable homogeneous hydrocolloid solution of pristine C60 with an average nanoparticle diameter of 50 nm was used in the experiments. Fluorescently labeled C60 was synthesized by covalently coupling C60 with rhodamine B isothiocyanate. Results: Confocal microscopy Results showed that leukemic Jurkat cells could efficiently take up Fullerene-C60 from the culture medium. Light-emitting diode light (100 mW cm-2, λ = 420–700 nm) was used to excite the accumulated C60. When leukemic Jurkat cells were exposed to a combination of C60 and visible light treatment, a time-dependent decrease in viability was detected. [1] |
| Molecular Weight | 720.64 |
| Formula | C60 |
| Cas No. | 99685-96-8 |
| Smiles | C=12C3=C4C=5C1C6=C7C=8C2=C9C%10=C3C=%11C%12=C4C%13=C%14C5C%15=C6C%16=C7C%17=C%18C8C9=C%19C%20=C%10C%11C%21=C%22C%12=C%13C%23=C%24C%14=C%15C%25=C%16C%26=C%17C=%27C%18=C%19C=%28C%20=C%21C=%29C%22=C%23C%30=C%24C%25=C%26C=%31C%27C%28C%29C%30%31 |
| Storage | keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: < 1 mg/mL, insoluble H2O: < 1 mg/mL, insoluble |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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