Shopping Cart

Your shopping cart is currently empty

BAY-0069

Name: BAY-0069
Brand: TargetMol
SKU: T67936
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T67936Cas No. 420826-65-9

BAY-0069 is a potent and selective PPARγ transactivator, inhibiting human PPARγ and murine PPARγ with IC50 values of 6.3 nM and 24 nM, respectively. BAY-0069 can be used in cancer research.

BAY-0069

🥰Excellent

Purity: 99.42%

Catalog No. T67936Cas No. 420826-65-9

BAY-0069 is a potent and selective PPARγ transactivator, inhibiting human PPARγ and murine PPARγ with IC50 values of 6.3 nM and 24 nM, respectively. BAY-0069 can be used in cancer research.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$34	In Stock	In Stock
10 mg	$54	In Stock	In Stock
25 mg	$121	In Stock	In Stock
50 mg	$191	In Stock	In Stock
100 mg	$289	In Stock	In Stock
200 mg	$411	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.42%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BAY-0069 is a potent and selective PPARγ transactivator, inhibiting human PPARγ and murine PPARγ with IC50 values of 6.3 nM and 24 nM, respectively. BAY-0069 can be used in cancer research.
Targets&IC50	PPARγ (human):6.3 nM, PPARγ (rat):24 nM, CYP2C8:4.3 μM
In vitro	BAY-0069 (0.0001, 0.001, 0.01, 0.01 and 1 μM; 7 days) leads to antiproliferative effects in the PPARγ-amplified cell line UM-UC-9.[1]
In vivo	BAY-0069 (1 μM; 1 h) exhibits superior microsomal stability, with a CL(b,hmic) of 0.47 L/h/kg in human liver microsomes and a CL(b,rhep) of 3.9 L/h/kg in rat liver hepatocytes.[1]

Chemical Properties

Molecular Weight	466.28
Formula	C₂₂H₁₆BrN₃O₄
Cas No.	420826-65-9
Smiles	N(C(=O)C1=CC(N(=O)=O)=CC=C1Br)C=2C=C3C(OC(=N3)C4=CC=C(CC)C=C4)=CC2
Relative Density.	1.530 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (193.02 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1446 mL	10.7232 mL	21.4463 mL	107.2317 mL
5 mM	0.4289 mL	2.1446 mL	4.2893 mL	21.4463 mL
10 mM	0.2145 mL	1.0723 mL	2.1446 mL	10.7232 mL
20 mM	0.1072 mL	0.5362 mL	1.0723 mL	5.3616 mL
50 mM	0.0429 mL	0.2145 mL	0.4289 mL	2.1446 mL
100 mM	0.0214 mL	0.1072 mL	0.2145 mL	1.0723 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc