Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 690.00 | |
500 mg | In stock | $ 1,450.00 |
Description | BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research. |
Targets&IC50 | PPARγ (human):6.3 nM, PPARγ (rat):24 nM, CYP2C8:4.3 μM |
In vitro | BAY-0069 (0.0001, 0.001, 0.01, 0.01 and 1 μM; 7 days) leads to antiproliferative effects in the PPARγ-amplified cell line UM-UC-9.[1] |
In vivo | BAY-0069 (1 μM; 1 h) shows excellent microsomal stability with CL(b,hmic) of 0.47 L/h/kg in human liver microsomes and CL(b,rhep) of 3.9 L/h/kg in rat liver hepatocytes.[1] |
Molecular Weight | 466.28 |
Formula | C22H16BrN3O4 |
CAS No. | 420826-65-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (193.0 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BAY-0069 420826-65-9 DNA Damage/DNA Repair Metabolism PPAR BAY0069 BAY 0069 CompoundBAY0069 inhibitor inhibit