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Mycaminosyltylonolide

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Catalog No. T67867Cas No. 61257-02-1

Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.

Mycaminosyltylonolide

Mycaminosyltylonolide

😃Good
Purity: 98.56%
Catalog No. T67867Cas No. 61257-02-1
Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$40-In Stock
5 mg$82-In Stock
10 mg$133-In Stock
25 mgPreferential-In Stock
50 mgPreferential-In Stock
1 mL x 10 mM (in DMSO)$107-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.56%
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Product Introduction

Bioactivity
Description
Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.
In vitro
Mycaminosyltylonolide(3µM) inhibits firefly luciferase mRNA translation in E. coli S30 [1]. Mycaminosyltylonolide(0-128 µg/mL) shows antibacterial activity with MIC values of 1, 1, 2, 2, 1, 64 µg/mL for S. aureus FDA209Pa, S. aureus Smitha, S. aureus KUB857c, S. epidermidis KUB795g, E. faecalis ATCC29212h, K. pneumoniae NCTC9632h, respectively [2].
Chemical Properties
Molecular Weight597.74
FormulaC31H51NO10
Cas No.61257-02-1
SmilesCC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@@H]1CO
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (50.19 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6730 mL8.3648 mL16.7297 mL83.6484 mL
5 mM0.3346 mL1.6730 mL3.3459 mL16.7297 mL
10 mM0.1673 mL0.8365 mL1.6730 mL8.3648 mL
20 mM0.0836 mL0.4182 mL0.8365 mL4.1824 mL
50 mM0.0335 mL0.1673 mL0.3346 mL1.6730 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

S. aureusOMTMycaminosyltylonolide
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