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Mycaminosyltylonolide

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Catalog No. T67867Cas No. 61257-02-1

Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.

Mycaminosyltylonolide

Mycaminosyltylonolide

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Purity: 98.56%
Catalog No. T67867Cas No. 61257-02-1
Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$40-In Stock
5 mg$82-In Stock
10 mg$133-In Stock
25 mgPreferential-In Stock
50 mgPreferential-In Stock
1 mL x 10 mM (in DMSO)$107-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.56%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Mycaminosyltylonolide is a macrolide antibiotic that is tylonolide having a beta-D-mycaminosyl residue attached at position 5. Mycaminosyltylonolide is a potent antibiotic with antibacterial activity and inhibits luciferase synthesis.
In vitro
Mycaminosyltylonolide(3µM) inhibits firefly luciferase mRNA translation in E. coli S30 [1]. Mycaminosyltylonolide(0-128 µg/mL) shows antibacterial activity with MIC values of 1, 1, 2, 2, 1, 64 µg/mL for S. aureus FDA209Pa, S. aureus Smitha, S. aureus KUB857c, S. epidermidis KUB795g, E. faecalis ATCC29212h, K. pneumoniae NCTC9632h, respectively [2].
Chemical Properties
Molecular Weight597.74
FormulaC31H51NO10
Cas No.61257-02-1
SmilesCC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@@H]1CO
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (50.19 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6730 mL8.3648 mL16.7297 mL83.6484 mL
5 mM0.3346 mL1.6730 mL3.3459 mL16.7297 mL
10 mM0.1673 mL0.8365 mL1.6730 mL8.3648 mL
20 mM0.0836 mL0.4182 mL0.8365 mL4.1824 mL
50 mM0.0335 mL0.1673 mL0.3346 mL1.6730 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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