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Amthamine 2HCl

🥰Excellent
Catalog No. T50112Cas No. 136604-58-5
Alias 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine 2HCl

5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, including fragile X syndrome, autism spectrum disorders, and addiction.

Amthamine 2HCl
Other Forms of Amthamine 2HCl:
Amthamine dihydrobromideT22570142457-00-9
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Amthamine 2HCl

🥰Excellent
Purity: 98.61%
Catalog No. T50112Alias 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine 2HClCas No. 136604-58-5
5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, including fragile X syndrome, autism spectrum disorders, and addiction.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$215In StockIn Stock
2 mg$323In StockIn Stock
5 mg$497In StockIn Stock
10 mg$723In StockIn Stock
25 mg$1,130In StockIn Stock
50 mg$1,520In StockIn Stock
100 mg$1,980In StockIn Stock
500 mg$3,970In Stock-
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.61%
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Product Introduction

Bioactivity
Description
5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, including fragile X syndrome, autism spectrum disorders, and addiction.
Synonyms5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine 2HCl
Chemical Properties
Molecular Weight230.159
FormulaC6H13Cl2N3S
Cas No.136604-58-5
SmilesCl.Cl.Cc1nc(N)sc1CCN
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 14.67 mg/mL (63.74 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3448 mL21.7241 mL43.4482 mL217.2411 mL
5 mM0.8690 mL4.3448 mL8.6896 mL43.4482 mL
10 mM0.4345 mL2.1724 mL4.3448 mL21.7241 mL
20 mM0.2172 mL1.0862 mL2.1724 mL10.8621 mL
50 mM0.0869 mL0.4345 mL0.8690 mL4.3448 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

5(2aminoethyl)4methyl1,3thiazol2amine dihydrochloride5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine5 (2 aminoethyl) 4 methyl 1,3 thiazol 2 amine dihydrochloride
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