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Lanosterol (Standard) is the analytical standard of Lanosterol, primarily used for quantitative analysis and metabolic research. Lanosterol is the first sterol intermediate in the cholesterol biosynthetic pathway, synthesized from squalene via squalene epoxidase. It plays a pivotal role in lipid homeostasis by inducing the ubiquitination and proteasomal degradation of HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the pathway. Beyond its metabolic function, Lanosterol exhibits potent molecular chaperone-like activity, inhibiting the aggregation and associated cytotoxicity of misfolded proteins linked to neurodegenerative diseases and cataracts.

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | $213 | 7-10 days | 7-10 days |
| Description | Lanosterol (Standard) is the analytical standard of Lanosterol, primarily used for quantitative analysis and metabolic research. Lanosterol is the first sterol intermediate in the cholesterol biosynthetic pathway, synthesized from squalene via squalene epoxidase. It plays a pivotal role in lipid homeostasis by inducing the ubiquitination and proteasomal degradation of HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the pathway. Beyond its metabolic function, Lanosterol exhibits potent molecular chaperone-like activity, inhibiting the aggregation and associated cytotoxicity of misfolded proteins linked to neurodegenerative diseases and cataracts. |
| Molecular Weight | 426.72 |
| Formula | C30H50O |
| Cas No. | 79-63-0 |
| Smiles | C[C@]12C3=C([C@]4(C)[C@@](CC3)(C(C)(C)[C@@H](O)CC4)[H])CC[C@]1(C)[C@@]([C@@H](CCC=C(C)C)C)(CC2)[H] |
| Relative Density. | 0.98g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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