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Camizestrant TFA

Catalog No. T11237L CAS T11237L

Synonyms: Camizestrant TFA(2222844-89-3 Free base), AZD-9833 TFA

Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Camizestrant TFA, CAS T11237L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 173.00
5 mg	In stock	$ 427.00
10 mg	In stock	$ 632.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,350.00
100 mg	In stock	$ 1,830.00
500 mg	In stock	$ 3,660.00
1 mL * 10 mM (in DMSO)	In stock	$ 448.00

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Purity: 98.9%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).
In vivo	Camizestrant TFA (oral administration; 0.2-50 mg/kg; 20 days) shows anti-tumour efficacy in human parental MCF7 mice xenograft. Camizestrant TFA (oral administration; 0.8-40 mg/kg; 30 days) decreases tumor growth. Camizestrant TFA gives almost complete tumour growth inhibition at the doses >10 mg/kg in mice[1].

Synonyms	Camizestrant TFA(2222844-89-3 Free base), AZD-9833 TFA
Molecular Weight	590.54
Formula	C26H29F7N6O2
CAS No.	T11237L

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 70 mg/mL (118.54 mM)

References and Literature

1. Bernard Christophe Barlaam, etal. Chemical compounds. Patent US20180111931.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Cancer Active Compound Library Drug Repurposing Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Clinical Compound Library Anti-Ovarian Cancer Compound Library Bioactive Compound Library Nuclear Receptor Compound Library Bioactive Compounds Library Max

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Camizestrant TFA T11237L Endocrinology/Hormones Estrogen Receptor/ERR Camizestrant TFA(2222844-89-3 Free base) AZD-9833 TFA inhibitor inhibit

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