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Camizestrant TFA

Name: Camizestrant TFA
Brand: TargetMol
SKU: T11237L
Price: 59 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11237L

Alias Camizestrant TFA(2222844-89-3 Free base), AZD-9833 TFA

Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).

Camizestrant TFA

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Purity: 99.85%

Catalog No. T11237LAlias Camizestrant TFA(2222844-89-3 Free base), AZD-9833 TFA

Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$59	-	In Stock
5 mg	$153	-	In Stock
10 mg	$227	-	In Stock
25 mg	$355	-	In Stock
50 mg	$476	-	In Stock
100 mg	$697	-	In Stock
200 mg	$997	-	In Stock
1 mL x 10 mM (in DMSO)	$161	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.85%

Appearance:Oil

Color:Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).
In vivo	Camizestrant TFA (oral administration; 0.2-50 mg/kg; 20 days) shows anti-tumour efficacy in human parental MCF7 mice xenograft. Camizestrant TFA (oral administration; 0.8-40 mg/kg; 30 days) decreases tumor growth. Camizestrant TFA gives almost complete tumour growth inhibition at the doses >10 mg/kg in mice[1].
Synonyms	Camizestrant TFA(2222844-89-3 Free base), AZD-9833 TFA

Chemical Properties

Molecular Weight	590.54
Formula	C₂₆H₂₉F₇N₆O₂
Smiles	FC(F)(F)CN1[C@H](C2=CC=C(C=N2)NC3CN(C3)CCCF)C4=C(C[C@H]1C)C5=C(NN=C5)C=C4.O=C(O)C(F)(F)F
Relative Density.	no data available

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 70 mg/mL (118.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6934 mL	8.4668 mL	16.9337 mL	84.6683 mL
5 mM	0.3387 mL	1.6934 mL	3.3867 mL	16.9337 mL
10 mM	0.1693 mL	0.8467 mL	1.6934 mL	8.4668 mL
20 mM	0.0847 mL	0.4233 mL	0.8467 mL	4.2334 mL
50 mM	0.0339 mL	0.1693 mL	0.3387 mL	1.6934 mL
100 mM	0.0169 mL	0.0847 mL	0.1693 mL	0.8467 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc