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GSK2324

Name: GSK2324
Brand: TargetMol
SKU: T27460
Price: 342 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T27460Cas No. 1020567-30-9

Alias GSK-2324, GSK 2324

GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.

GSK2324

🥰Excellent

Purity: 99.02%

Catalog No. T27460Alias GSK-2324, GSK 2324Cas No. 1020567-30-9

GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.

Pack Size	Price	Availability
1 mg	$342	In Stock
5 mg	$828	In Stock
10 mg	$1,130	In Stock
25 mg	$1,680	In Stock
50 mg	$2,290	In Stock
100 mg	$2,970	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.02%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.
Synonyms	GSK-2324, GSK 2324

Chemical Properties

Molecular Weight	533.4
Formula	C₂₉H₂₂Cl₂N₂O₄
Cas No.	1020567-30-9
Smiles	C(OC1=CC=C(C=C1)C2=CC3=C(C=C2)N=C(C(O)=O)C=C3)C=4C(=NOC4C(C)C)C5=C(Cl)C=CC=C5Cl
Relative Density.	1.351 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (187.48 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8748 mL	9.3738 mL	18.7477 mL	93.7383 mL
5 mM	0.3750 mL	1.8748 mL	3.7495 mL	18.7477 mL
10 mM	0.1875 mL	0.9374 mL	1.8748 mL	9.3738 mL
20 mM	0.0937 mL	0.4687 mL	0.9374 mL	4.6869 mL
50 mM	0.0375 mL	0.1875 mL	0.3750 mL	1.8748 mL
100 mM	0.0187 mL	0.0937 mL	0.1875 mL	0.9374 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc