Shopping Cart
Remove All
Your shopping cart is currently empty
CAY10580
Copy Product Info
😃Good
Catalog No. T40738Cas No. 64054-40-6
CAY10580 is a selective prostaglandin EP4 receptor agonist (Ki=35 nM) and PGE2 analog that prevents diet-induced hypercholesterolemia.
CAY10580
Copy Product Info😃Good
Catalog No. T40738Cas No. 64054-40-6
CAY10580 is a selective prostaglandin EP4 receptor agonist (Ki=35 nM) and PGE2 analog that prevents diet-induced hypercholesterolemia.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 μg | $258 | - | In Stock | |
| 1 mg | $482 | 35 days | 35 days | |
| 5 mg | $1,960 | 35 days | 35 days | |
| 10 mg | $3,500 | 35 days | 35 days |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Appearance:Liquid
Color:Transparent
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | CAY10580 is a selective prostaglandin EP4 receptor agonist (Ki=35 nM) and PGE2 analog that prevents diet-induced hypercholesterolemia. |
| Targets&IC50 | EP2 receptor:3000 nM (Ki), EP4 receptor:35 nM (Ki), EP3 receptor:2000 nM (Ki), EP1 receptor:>3000 nM (Ki) |
| In vitro | CAY10580 (200 μg/kg; intraperitoneal injection; once daily for three weeks) prevents diet-induced hypercholesterolemia by enhancing endogenous bile acid synthesis and fecal excretion [3]. |
| In vivo | CAY10580, administered intraperitoneally at a dosage of 200 μg/kg body weight daily for three weeks, effectively combats diet-induced hypercholesterolemia, promotes endogenous bile acid synthesis, and increases their excretion in feces. In a study using six-week-old male EP4 +/+ mice challenged with a high-fat diet, these mice exhibited a 28.5% reduction in total cholesterol levels compared to the control group, with levels decreasing from 137.4 to 98.2 mg/dl, thereby nearly normalizing plasma cholesterol concentrations. |
| Molecular Weight | 341.49 |
| Formula | C19H35NO4 |
| Cas No. | 64054-40-6 |
| Smiles | O=C(O)CCCCCCN1C(=O)CCC1CCC(O)CCCCC |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy CAY10580 | purchase CAY10580 | CAY10580 cost | order CAY10580 | CAY10580 chemical structure | CAY10580 in vivo | CAY10580 in vitro | CAY10580 formula | CAY10580 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.