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WDR5-47

Name: WDR5-47
Brand: TargetMol
SKU: T67697
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T67697Cas No. 1422389-91-0

WDR5-47 is a potent small molecule to disturb the interaction of MLL1-WDR5 with IC50 value of 0.3μM.

WDR5-47

🥰Excellent

Purity: 98.15%

Catalog No. T67697Cas No. 1422389-91-0

WDR5-47 is a potent small molecule to disturb the interaction of MLL1-WDR5 with IC50 value of 0.3μM.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$82	In Stock	In Stock
5 mg	$188	In Stock	In Stock
10 mg	$277	In Stock	In Stock
25 mg	$413	In Stock	In Stock
50 mg	$580	In Stock	In Stock
100 mg	$791	In Stock	In Stock
200 mg	$1,060	-	In Stock
1 mL x 10 mM (in DMSO)	$205	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.15%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	WDR5-47 is a potent small molecule to disturb the interaction of MLL1-WDR5 with IC50 value of 0.3μM.
Targets&IC50	MLL1-WDR5:0.3 μM

Chemical Properties

Molecular Weight	406.84
Formula	C₁₉H₂₀ClFN₄O₃
Cas No.	1422389-91-0
Smiles	N(C(=O)C1=C(Cl)C(C)=C(F)C=C1)C2=C(C=CC(N(=O)=O)=C2)N3CCN(C)CC3
Relative Density.	1.374 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (61.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4580 mL	12.2898 mL	24.5797 mL	122.8984 mL
5 mM	0.4916 mL	2.4580 mL	4.9159 mL	24.5797 mL
10 mM	0.2458 mL	1.2290 mL	2.4580 mL	12.2898 mL
20 mM	0.1229 mL	0.6145 mL	1.2290 mL	6.1449 mL
50 mM	0.0492 mL	0.2458 mL	0.4916 mL	2.4580 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc