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Anti-MRSA agent 36 (Compound III13) is a potent antibacterial compound with significant anti-MRSA activity (MIC = 1 μg/mL). It targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. The agent offers advantages such as low cytotoxicity, low hemolytic activity, reduced likelihood of inducing resistance, and excellent plasma stability. Anti-MRSA agent 36 is applicable for research in skin abscess and systemic infection models.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | Anti-MRSA agent 36 (Compound III13) is a potent antibacterial compound with significant anti-MRSA activity (MIC = 1 μg/mL). It targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. The agent offers advantages such as low cytotoxicity, low hemolytic activity, reduced likelihood of inducing resistance, and excellent plasma stability. Anti-MRSA agent 36 is applicable for research in skin abscess and systemic infection models. |
| Molecular Weight | 603.57 |
| Formula | C29H35BrN2O5S |
| Cas No. | 3096122-10-7 |
| Smiles | [Br-].O=C1OC=2C(C=C1)=CC=3C=COC3C2OCCCCCSC4=CC=[N+](C=C4)CC(=O)NCCCCCC |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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