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OLDA (Synonyms: N-Oleoyldopamine)

Name: OLDA
Brand: TargetMol
SKU: T23105
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T23105 Copy Product Info

Purity: 99.88%

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OLDA (N-oleoyldopamine) is an endogenous lipid modulator found in the brain and a potent TRPV1 receptor agonist (EC50 = 36 nM). It regulates nociceptive neurotransmission and thermal homeostasis at the physiological level by activating vanilloid receptors to induce intracellular calcium release.

OLDA

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Catalog No. T23105

Synonyms N-Oleoyldopamine

Cas No. 105955-11-1

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Pack Size	Price	USA Stock	Global Stock
5 mg	$31	-	In Stock
10 mg	$58	-	In Stock
25 mg	$94	-	In Stock
50 mg	$138	-	In Stock
1 mL x 10 mM (in DMSO)	$35	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.88%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	OLDA (N-oleoyldopamine) is an endogenous lipid modulator found in the brain and a potent TRPV1 receptor agonist (EC50 = 36 nM). It regulates nociceptive neurotransmission and thermal homeostasis at the physiological level by activating vanilloid receptors to induce intracellular calcium release.
In vivo	OLDA, an endogenous capsaicin-like lipid, exerts cardioprotective effects in ischemia-reperfusion models via activation of TRPV1 channels [1].
Synonyms	N-Oleoyldopamine

Chemical Properties

Molecular Weight	417.62
Formula	C₂₆H₄₃NO₃
Cas No.	105955-11-1
Smiles	C(CNC(CCCCCCC/C=C\CCCCCCCC)=O)C1=CC(O)=C(O)C=C1
Relative Density.	1.004g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (191.56 mM), Sonication is recommmended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3945 mL	11.9726 mL	23.9452 mL	119.7261 mL
5 mM	0.4789 mL	2.3945 mL	4.7890 mL	23.9452 mL
10 mM	0.2395 mL	1.1973 mL	2.3945 mL	11.9726 mL
20 mM	0.1197 mL	0.5986 mL	1.1973 mL	5.9863 mL
50 mM	0.0479 mL	0.2395 mL	0.4789 mL	2.3945 mL
100 mM	0.0239 mL	0.1197 mL	0.2395 mL	1.1973 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc