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Anti-IL-13 Antibody (M1295)
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Catalog No. T9901A-1296
Alias M1295
Anti-IL-13 Antibody (M1295) is a potent neutralizing antibody targeting human interleukin-13 (IL-13), acting by blocking the binding of IL-13 to its receptor complex. The compound is an essential tool for investigating Type 2 immune responses and the pathogenesis of bronchial asthma and atopic dermatitis, aiming to inhibit allergic inflammatory processes by downregulating IL-13-mediated signaling cascades.
Anti-IL-13 Antibody (M1295)
Anti-IL-13 Antibody (M1295)
Copy Product Info🥰Excellent
Catalog No. T9901A-1296Alias M1295
Anti-IL-13 Antibody (M1295) is a potent neutralizing antibody targeting human interleukin-13 (IL-13), acting by blocking the binding of IL-13 to its receptor complex. The compound is an essential tool for investigating Type 2 immune responses and the pathogenesis of bronchial asthma and atopic dermatitis, aiming to inhibit allergic inflammatory processes by downregulating IL-13-mediated signaling cascades.
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| Description | Anti-IL-13 Antibody (M1295) is a potent neutralizing antibody targeting human interleukin-13 (IL-13), acting by blocking the binding of IL-13 to its receptor complex. The compound is an essential tool for investigating Type 2 immune responses and the pathogenesis of bronchial asthma and atopic dermatitis, aiming to inhibit allergic inflammatory processes by downregulating IL-13-mediated signaling cascades. |
| Targets&IC50 | IL-13:52 pM(Kd) |
| In vitro | In binding kinetics assays targeting human IL-13, Anti-IL-13 Antibody (M1295) exhibited high affinity with a Kd of 52 pM and inhibited STAT6 phosphorylation and TF-1 cell proliferation [1]. |
| Synonyms | M1295 |
| Clone | M1295 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | IL-13 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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