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MK-0249 FA

🥰Excellent
Catalog No. T12054L
Alias MK-0249 FA(862309-06-6 Free base)

MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults.

MK-0249 FA

MK-0249 FA

🥰Excellent
Purity: 99.98%
Catalog No. T12054LAlias MK-0249 FA(862309-06-6 Free base)
MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults.
Pack SizePriceAvailabilityQuantity
1 mg$195In Stock
5 mg$828In Stock
10 mg$1,090In Stock
25 mg$1,650In Stock
50 mg$2,230In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.98%
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Product Introduction

Bioactivity
Description
MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults.
Targets&IC50
H3 receptor (rat):33 nM (Ki), H3 receptor (human):6.8 nM (Ki), H3 receptor (human):1.7 nM
AliasMK-0249 FA(862309-06-6 Free base)
Chemical Properties
Molecular Weight477.48
FormulaC24H26F3N3O4
SmilesO=C1C2=C(C=CC=C2C(F)(F)F)N=C(C)N1C3=CC=C(C=C3)OCCCN4CCCC4.[H]C(O)=O
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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