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Tetrahexyldecyl ascorbate
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Catalog No. T20174Cas No. 183476-82-6
Alias Nikkol VC-IP, IPAA, BV-OSC, Ascorbyl tetra-2-hexyldecanoat
Tetrahexyldecyl ascorbate (BV-OSC) is a lipophilic precursor of ascorbic acid, a more stable and permeable form of vitamin C. It is a potent anti-photo-aging and anti-hyperpigmentation antioxidant that inhibits MMP enzyme activity.
Tetrahexyldecyl ascorbate
😃Good
Catalog No. T20174Alias Nikkol VC-IP, IPAA, BV-OSC, Ascorbyl tetra-2-hexyldecanoatCas No. 183476-82-6
Tetrahexyldecyl ascorbate (BV-OSC) is a lipophilic precursor of ascorbic acid, a more stable and permeable form of vitamin C. It is a potent anti-photo-aging and anti-hyperpigmentation antioxidant that inhibits MMP enzyme activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 g | $34 | 7-10 days | |
| 5 g | $97 | 7-10 days | |
| 1 mL x 10 mM (in DMSO) | $29 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tetrahexyldecyl ascorbate (BV-OSC) is a lipophilic precursor of ascorbic acid, a more stable and permeable form of vitamin C. It is a potent anti-photo-aging and anti-hyperpigmentation antioxidant that inhibits MMP enzyme activity. |
| In vitro | Tetrahexyldecyl ascorbate, either alone or in combination with AZ, was applied to human keratinocytes (HaCaT) and dermal fibroblasts (nHDF, aHDF), and incubated for 0.5 to 3 hours. After treatment, cell viability was assessed using CCK-8, ELISA, and gene chip technologies. The Results showed that Tetrahexyldecyl ascorbate reduced cell viability under oxidative stress, while its combination with AZ significantly enhanced cell activity. The combination therapy upregulated genes related to phospholipid homeostasis and keratinocyte differentiation, inhibited the expression of MMP1 and MMP7, and promoted collagen synthesis in dermal fibroblasts [1]. |
| Alias | Nikkol VC-IP, IPAA, BV-OSC, Ascorbyl tetra-2-hexyldecanoat |
| Molecular Weight | 1129.76 |
| Formula | C70H128O10 |
| Cas No. | 183476-82-6 |
| Smiles | [C@H](OC(C(CCCCCCCC)CCCCCC)=O)(COC(C(CCCCCCCC)CCCCCC)=O)[C@@]1(C(OC(C(CCCCCCCC)CCCCCC)=O)=C(OC(C(CCCCCCCC)CCCCCC)=O)C(=O)O1)[H] |
| Relative Density. | 0.928-0.941 g/cm3 at 20℃ |
Storage & Solubility Information
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 180.00 mg/mL (159.33 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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