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AhR agonist 2
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Catalog No. T61244
AhR agonist 2 is a triazolopyridine derivative and novel aryl hydrocarbon receptor (AhR) agonist with the advantages of being orally bioavailable and highly potent (EC50=0.03 nM), inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair for the treatment of psoriasis.
AhR agonist 2
😃Good
Catalog No. T61244
AhR agonist 2 is a triazolopyridine derivative and novel aryl hydrocarbon receptor (AhR) agonist with the advantages of being orally bioavailable and highly potent (EC50=0.03 nM), inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair for the treatment of psoriasis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $58 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | AhR agonist 2 is a triazolopyridine derivative and novel aryl hydrocarbon receptor (AhR) agonist with the advantages of being orally bioavailable and highly potent (EC50=0.03 nM), inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair for the treatment of psoriasis. |
| Molecular Weight | 353.01 |
| Formula | C12H7Br2N3 |
| Smiles | BrC=1C=CC(=CC1)C=2N=C3C=CC(Br)=CN3N2 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 16 mg/mL (45.32 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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