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F7H

Name: F7H
Brand: TargetMol
SKU: T77692
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77692Cas No. 897109-93-2

F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.

F7H

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Purity: 99.85%

Catalog No. T77692Cas No. 897109-93-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$40	In Stock	In Stock
5 mg	$106	In Stock	In Stock
10 mg	$163	In Stock	In Stock
25 mg	$278	In Stock	In Stock
50 mg	$417	In Stock	In Stock
100 mg	$593	In Stock	In Stock
500 mg	$1,270	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.85%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.
Targets&IC50	Frizzled receptor:1.25 μM

Chemical Properties

Molecular Weight	463.55
Formula	C₂₄H₁₈FN₃O₂S₂
Cas No.	897109-93-2
Smiles	O=C(NC1=CC=C(SCC(=O)NC2=NC(=CS2)C=3C=CC=CC3)C=C1)C4=CC=C(F)C=C4
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (107.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1573 mL	10.7863 mL	21.5726 mL	107.8632 mL
5 mM	0.4315 mL	2.1573 mL	4.3145 mL	21.5726 mL
10 mM	0.2157 mL	1.0786 mL	2.1573 mL	10.7863 mL
20 mM	0.1079 mL	0.5393 mL	1.0786 mL	5.3932 mL
50 mM	0.0431 mL	0.2157 mL	0.4315 mL	2.1573 mL
100 mM	0.0216 mL	0.1079 mL	0.2157 mL	1.0786 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc