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F7H

Name: F7H
Brand: TargetMol
SKU: T77692
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77692Cas No. 897109-93-2

F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.

F7H

🥰Excellent

Purity: 99.85%

Catalog No. T77692Cas No. 897109-93-2

Pack Size	Price	Availability
1 mg	$40	In Stock
5 mg	$106	In Stock
10 mg	$163	In Stock
25 mg	$278	In Stock
50 mg	$417	In Stock
100 mg	$593	In Stock
500 mg	$1,270	In Stock

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Batch Information

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Purity:99.85%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, with potential antitumor and bacteriostatic activity.
Targets&IC50	Frizzled receptor:1.25 μM

Chemical Properties

Molecular Weight	463.55
Formula	C₂₄H₁₈FN₃O₂S₂
Cas No.	897109-93-2
Smiles	O=C(NC1=CC=C(SCC(=O)NC2=NC(=CS2)C=3C=CC=CC3)C=C1)C4=CC=C(F)C=C4
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (107.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1573 mL	10.7863 mL	21.5726 mL	107.8632 mL
5 mM	0.4315 mL	2.1573 mL	4.3145 mL	21.5726 mL
10 mM	0.2157 mL	1.0786 mL	2.1573 mL	10.7863 mL
20 mM	0.1079 mL	0.5393 mL	1.0786 mL	5.3932 mL
50 mM	0.0431 mL	0.2157 mL	0.4315 mL	2.1573 mL
100 mM	0.0216 mL	0.1079 mL	0.2157 mL	1.0786 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc