Shopping Cart

Remove All
Your shopping cart is currently empty

IRL-1038 TFA

Name: IRL-1038 TFA
Brand: TargetMol
SKU: TP2262L1
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. TP2262L1

Alias IRL-1038 TFA(144602-02-8 Free base)

IRL-1038 TFA is a selective and potent endothelin B (ETB) receptor antagonist that inhibits endothelin-induced endothelium-dependent relaxation and can be used in the study of cardiovascular disease.

IRL-1038 TFA

😃Good

Purity: 98.79%

Catalog No. TP2262L1Alias IRL-1038 TFA(144602-02-8 Free base)

IRL-1038 TFA is a selective and potent endothelin B (ETB) receptor antagonist that inhibits endothelin-induced endothelium-dependent relaxation and can be used in the study of cardiovascular disease.

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$50	Backorder
10 mg	$70	Backorder

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.79%

Resource Download

COA HPLC MS

Product Introduction

Bioactivity

Description	IRL-1038 TFA is a selective and potent endothelin B (ETB) receptor antagonist that inhibits endothelin-induced endothelium-dependent relaxation and can be used in the study of cardiovascular disease.
Synonyms	IRL-1038 TFA(144602-02-8 Free base)

Chemical Properties

Molecular Weight	1523.7
Formula	C₇₀H₉₃F₃N₁₄O₁₇S₂
Smiles	O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC1)N)=O)C(C)C)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)N[C@@H](CC4=CN=CN4)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Color	White
Appearance	Solid
Sequence	Cys(1)-Val-DL-Tyr-Phe-DL-Cys(1)-His-Leu-Asp-Ile-Ile-Trp
Sequence Short	CVYFCHLDIIW

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc