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BAY-784 is a potent gonadotropin-releasing hormone receptor (GnRH-R) antagonist that exhibits strong inhibitory activity with IC50 values of 21 nM for human GnRH-R and 24 nM for rat GnRH-R, BAY-784 is widely applied in endocrine research to study GnRH signaling, reproductive hormone regulation, and therapeutic modulation of hormone-dependent physiological and pathological processes.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $92 | - | In Stock | |
| 5 mg | $225 | - | In Stock | |
| 10 mg | $335 | - | In Stock | |
| 25 mg | $558 | - | In Stock |
| Description | BAY-784 is a potent gonadotropin-releasing hormone receptor (GnRH-R) antagonist that exhibits strong inhibitory activity with IC50 values of 21 nM for human GnRH-R and 24 nM for rat GnRH-R, BAY-784 is widely applied in endocrine research to study GnRH signaling, reproductive hormone regulation, and therapeutic modulation of hormone-dependent physiological and pathological processes. |
| Targets&IC50 | GnRHR:21 nM |
| In vivo | Method: BAY-784 was administered orally at 0.5, 3, 10, or 30 mg/kg as a single dose in ovariectomized rats. Result: BAY-784 reduced plasma luteinizing hormone levels in a dose-dependent manner[1]. |
| Synonyms | BAY-784, BAY784, BAY 784 |
| Molecular Weight | 672.11 |
| Formula | C29H26ClF4N3O5S2 |
| Cas No. | 1631164-24-3 |
| Smiles | S(=O)(=O)(N1[C@H](C2(C=3C1=CC=C(C(NCC4=C(Cl)C=C(C(F)(F)F)C=N4)=O)C3)CCS(=O)(=O)CC2)C5CC5)C6=CC=C(F)C=C6 |
| Relative Density. | 1.60 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 32 mg/mL (47.61 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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