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Verubulin

Name: Verubulin
Brand: TargetMol
SKU: T17229
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T17229Cas No. 827031-83-4

Alias MX-128495, MPC-6827, MPC6827, MPC 6827, EP-90745

Verubulin (MPC 6827) is a potent microtubule blocker with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts, and can be used to image microtubules (MTs) using positron emission tomography (PET).

Verubulin

🥰Excellent

Purity: 99.98%

Catalog No. T17229Alias MX-128495, MPC-6827, MPC6827, MPC 6827, EP-90745Cas No. 827031-83-4

Pack Size	Price	Availability
5 mg	$34	In Stock
10 mg	$46	In Stock
25 mg	$71	In Stock
50 mg	$98	In Stock
100 mg	$148	In Stock
500 mg	$363	In Stock
1 mL x 10 mM (in DMSO)	$41	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.98%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Verubulin (MPC 6827) is a potent microtubule blocker with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts, and can be used to image microtubules (MTs) using positron emission tomography (PET).
Synonyms	MX-128495, MPC-6827, MPC6827, MPC 6827, EP-90745

Chemical Properties

Molecular Weight	279.34
Formula	C₁₇H₁₇N₃O
Cas No.	827031-83-4
Smiles	N=1C(=NC(=C2C=CC=CC12)N(C3=CC=C(OC)C=C3)C)C
Relative Density.	1.189 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (447.48 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (14.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5799 mL	17.8993 mL	35.7987 mL	178.9933 mL
5 mM	0.7160 mL	3.5799 mL	7.1597 mL	35.7987 mL
10 mM	0.3580 mL	1.7899 mL	3.5799 mL	17.8993 mL
20 mM	0.1790 mL	0.8950 mL	1.7899 mL	8.9497 mL
50 mM	0.0716 mL	0.3580 mL	0.7160 mL	3.5799 mL
100 mM	0.0358 mL	0.1790 mL	0.3580 mL	1.7899 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc