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Anti-CLDN6 Antibody (AB1-11)
(Synonyms: AB1-11) Copy Product Info
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Synonyms: AB1-11
Catalog No. T9901A-1251 Copy Product Info
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Anti-CLDN6 Antibody (AB1-11) is a humanized monoclonal antibody targeting Claudin-6 (CLDN6). CLDN6 is a tight junction protein and an oncofetal antigen typically expressed in fetal tissues but virtually absent in normal adult tissues, while frequently re-expressed in various solid tumors such as ovarian cancer, germ cell tumors, gastric cancer, and lung cancer. This antibody specifically binds to the extracellular loops of CLDN6 and exerts potent anti-tumor activity by inducing antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Due to its high tumor specificity, this antibody serves as an ideal tool for developing targeted therapies, including ADCs or bispecific antibodies.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-CLDN6 Antibody (AB1-11) is a humanized monoclonal antibody targeting Claudin-6 (CLDN6). CLDN6 is a tight junction protein and an oncofetal antigen typically expressed in fetal tissues but virtually absent in normal adult tissues, while frequently re-expressed in various solid tumors such as ovarian cancer, germ cell tumors, gastric cancer, and lung cancer. This antibody specifically binds to the extracellular loops of CLDN6 and exerts potent anti-tumor activity by inducing antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Due to its high tumor specificity, this antibody serves as an ideal tool for developing targeted therapies, including ADCs or bispecific antibodies. |
| Synonyms | AB1-11 |
| Clone | AB1-11 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CLDN6 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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