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Tyrosylleucine TFA

Name: Tyrosylleucine TFA
Brand: TargetMol
SKU: T40778
Rating: 4.5 (1 reviews)

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Catalog No. T40778Cas No. 66852-01-5

Alias Tyr-Leu TFA

Tyrosylleucine (Tyr-Leu, YL) TFA is a dipeptide compound with potent antidepressant-like activity and demonstrates effective modulation of depressive symptoms when administered orally.

Tyrosylleucine TFA

😃Good

Catalog No. T40778Alias Tyr-Leu TFACas No. 66852-01-5

Tyrosylleucine (Tyr-Leu, YL) TFA is a dipeptide compound with potent antidepressant-like activity and demonstrates effective modulation of depressive symptoms when administered orally.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$39	7-10 days	7-10 days
10 mg	$57	7-10 days	7-10 days
25 mg	$94	7-10 days	7-10 days
50 mg	$139	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Tyrosylleucine (Tyr-Leu, YL) TFA is a dipeptide compound with potent antidepressant-like activity and demonstrates effective modulation of depressive symptoms when administered orally.
In vitro	Tyrosylleucine (Tyr-Leu, YL) elevates the number of c-Fos expressing cells, indicative of neuronal activity, within the hippocampal dentate gyrus[1].
In vivo	Tyrosylleucine (Tyr-Leu, YL) demonstrates strong anxiolytic-like effects in a dose-dependent manner (0.1-1 mg/kg, i.p.)[2].
Synonyms	Tyr-Leu TFA

Chemical Properties

Molecular Weight	408.374
Formula	C₁₇H₂₃F₃N₂O₆
Cas No.	66852-01-5
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tyrosylleucine TFA