Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shishijimicin C, a novel antitumor agent isolated from the ascidian Didemnum proliferum, exhibits highly potent cytotoxicities and anti-tumor activities. This compound also serves as a click chemistry reagent, featuring an alkyne group that can partake in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
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Description | Shishijimicin C, a novel antitumor agent isolated from the ascidian Didemnum proliferum, exhibits highly potent cytotoxicities and anti-tumor activities. This compound also serves as a click chemistry reagent, featuring an alkyne group that can partake in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. |
In vitro | Shishijimicin C (compound 3) exhibits potent cytotoxic activity, outstripping the efficacy of both adriamycin and etoposide. Its notable action against cancer cells, particularly P388 leukemia cells, highlights its potential as a therapeutic agent. Compound 3 does this by targeting the DNA within cancer cells, causing severe damage and subsequently triggering cell death. This mechanism underpins its proposed use as an anticancer drug. |
Molecular Weight | N/A |
CAS No. | 503860-52-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Shishijimicin C 503860-52-4 inhibitor inhibit