store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 700.00 | |
5 mg | In stock | $ 1,800.00 |
Description | CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease. |
In vitro | In cell lines expressing M1 receptors, CDD0102 (CDD-0102) is an efficacious muscarinic agonist. CDD0102 exhibits much lower activity at M3 and M5 receptors[1]. |
In vivo | Following i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. The LD50 of CDD0102 is 190 mg/kg in toxicological studies after i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration after oral administration at a dose of 10 mg/kg. No side effects are observed at this dose[1]. |
Synonyms | CDD0102A HCl |
Molecular Weight | 216.67 |
Formula | C8H13ClN4O |
CAS No. | 1196130-86-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CDD0102 HCl 1196130-86-5 Neuroscience AChR CDD0102A HCl inhibitor inhibit