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6-O-Caffeoylarbutin
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Catalog No. TN1320Cas No. 136172-60-6
Alias Robustaside B
6-O-Caffeoylarbutin (Robustaside B) is a natural antioxidant capable of inducing mitochondrial membrane permeability transition. It modulates the SIRT1/PI3K/AKT/NF-κB pathway, thereby ameliorating liver injury and symptoms of ischaemic stroke in mice.
6-O-Caffeoylarbutin
😃Good
Purity: 99.97%
Catalog No. TN1320Alias Robustaside BCas No. 136172-60-6
6-O-Caffeoylarbutin (Robustaside B) is a natural antioxidant capable of inducing mitochondrial membrane permeability transition. It modulates the SIRT1/PI3K/AKT/NF-κB pathway, thereby ameliorating liver injury and symptoms of ischaemic stroke in mice.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $893 | - | In Stock | |
| 5 mg | $1,820 | - | In Stock | |
| 10 mg | $2,450 | - | In Stock | |
| 25 mg | $3,630 | - | In Stock | |
| 50 mg | $4,890 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.97%
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Product Introduction
Bioactivity
Chemical Properties
| Description | 6-O-Caffeoylarbutin (Robustaside B) is a natural antioxidant capable of inducing mitochondrial membrane permeability transition. It modulates the SIRT1/PI3K/AKT/NF-κB pathway, thereby ameliorating liver injury and symptoms of ischaemic stroke in mice. |
| In vitro | 6-O-Caffeoylarbutin (Robustaside B) decreased the amount of TBARS produced during lipid peroxidation induced by the Fe2+/ascorbate system in rat liver mitochondria in vitro in a concentration-dependent manner. Varying concentrations of robustaside B (0.05, 0.1, 0.2, 0.25, 0.5, 0.75, and 1 mM) significantly reduced the amount of TBARS generated by 85.3, 86.4, 86.0, 86.1, 86.0, 86.0, and 86.0%, respectively [1]. |
| Synonyms | Robustaside B |
| Molecular Weight | 434.39 |
| Formula | C21H22O10 |
| Cas No. | 136172-60-6 |
| Smiles | O([C@@H]1O[C@H](COC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@@H](O)[C@H](O)[C@H]1O)C3=CC=C(O)C=C3 |
| Relative Density. | 1.553 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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