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AC-55649

Name: AC-55649
Brand: TargetMol
SKU: T14090
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14090Cas No. 59662-49-6

AC-55649 is a potent and highly isoform-selective agonist of the human RARβ2 receptor, characterized by a pEC50 of 6.9.

AC-55649

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Purity: 99.98%

Catalog No. T14090Cas No. 59662-49-6

AC-55649 is a potent and highly isoform-selective agonist of the human RARβ2 receptor, characterized by a pEC50 of 6.9.

Pack Size	Price	Availability
10 mg	$37	In Stock
25 mg	$78	In Stock
50 mg	$117	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.98%

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	AC-55649 is a potent and highly isoform-selective agonist of the human RARβ2 receptor, characterized by a pEC50 of 6.9.
Targets&IC50	RARβ2:6.9 （pEC50）
In vitro	AC-55649 is a potent and selective activator of RARβ2 transcriptional activity[2]. AC-55649 is a potent, highly isoform-selective agonist at the human RARβ2 receptor, with a pEC50 of 6.9[1].

Chemical Properties

Molecular Weight	310.43
Formula	C₂₁H₂₆O₂
Cas No.	59662-49-6
Smiles	CCCCCCCCc1ccc(cc1)-c1ccc(cc1)C(O)=O
Relative Density.	1.037 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90.0 mg/mL (289.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2213 mL	16.1067 mL	32.2134 mL	161.0669 mL
5 mM	0.6443 mL	3.2213 mL	6.4427 mL	32.2134 mL
10 mM	0.3221 mL	1.6107 mL	3.2213 mL	16.1067 mL
20 mM	0.1611 mL	0.8053 mL	1.6107 mL	8.0533 mL
50 mM	0.0644 mL	0.3221 mL	0.6443 mL	3.2213 mL
100 mM	0.0322 mL	0.1611 mL	0.3221 mL	1.6107 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc