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R715 TFA(185052-09-9 free base)

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Catalog No. TP1933
Alias R 715

R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.

R715 TFA(185052-09-9 free base)
Other Forms of R715 TFA(185052-09-9 free base):
R 715 TFAT83688
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R715 TFA(185052-09-9 free base)

🥰Excellent
Catalog No. TP1933Alias R 715
R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.
Pack SizePriceAvailabilityQuantity
1 mg$152In Stock
5 mg$326In Stock
10 mg$490In Stock
25 mg$783In Stock
50 mg$1,090In Stock
100 mg$1,480In Stock
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Purity:>99.99%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.
Targets&IC50
Bradykinin B1:8.49(pA2)
SynonymsR 715
Chemical Properties
Molecular Weight1254.36
FormulaC59H82F3N13O14
SmilesCC[C@H](C)[C@@H](C(=O)O)NC(=O)[C@@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)C.OC(C(F)(F)F)=O
Relative Density.no data available
ColorWhite
Appearancesolid
SequenceAc-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D-2Nal-Ile-OH
Sequence ShortKRPPGFSXI
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 5 mg/mL (3.99 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.7972 mL3.9861 mL7.9722 mL39.8610 mL

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Keywords

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