Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are 'effector caspases' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 73.00 | |
10 mg | 35 days | $ 540.00 |
Description | CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are 'effector caspases' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406. |
Molecular Weight | 544.54 |
Formula | C27H23F3N2O5S |
CAS No. | 2108603-03-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 25 mg/mL
Ethanol: 0.05 mg/mL
DMF:PBS (pH 7.2) (1:2): 0.5 mg/mL
DMSO: 10 mg/mL
You can also refer to dose conversion for different animals. More
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CAY10406 2108603-03-6 CAY-10406 CAY 10406 inhibitor inhibit