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Rafabegron

Name: Rafabegron
Brand: TargetMol
SKU: T34256
Price: 290 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T34256Cas No. 244081-42-3

Alias TAK-677, TAK677, TAK 677, AD-9677, AD9677, AD 9677

Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.

Rafabegron

🥰Excellent

Purity: 99.21%

Catalog No. T34256Alias TAK-677, TAK677, TAK 677, AD-9677, AD9677, AD 9677Cas No. 244081-42-3

Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.

Pack Size	Price	Availability
1 mg	$290	In Stock
5 mg	$713	In Stock
10 mg	$987	In Stock
25 mg	$1,480	In Stock
50 mg	$1,980	In Stock
100 mg	$2,730	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.21%

ee:100%

Resource Download

COA CSFC HNMR LCMS ORP

Product Introduction

Bioactivity

Description	Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.
Synonyms	TAK-677, TAK677, TAK 677, AD-9677, AD9677, AD 9677

Chemical Properties

Molecular Weight	402.87
Formula	C₂₁H₂₃ClN₂O₄
Cas No.	244081-42-3
Smiles	O(CC(O)=O)C1=C2C(C(C[C@H](NC[C@H](O)C3=CC(Cl)=CC=C3)C)=CN2)=CC=C1
Relative Density.	1.345g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (111.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4822 mL	12.4110 mL	24.8219 mL	124.1095 mL
5 mM	0.4964 mL	2.4822 mL	4.9644 mL	24.8219 mL
10 mM	0.2482 mL	1.2411 mL	2.4822 mL	12.4110 mL
20 mM	0.1241 mL	0.6205 mL	1.2411 mL	6.2055 mL
50 mM	0.0496 mL	0.2482 mL	0.4964 mL	2.4822 mL
100 mM	0.0248 mL	0.1241 mL	0.2482 mL	1.2411 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc