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Cauloside A

Name: Cauloside A
Brand: TargetMol
SKU: TN1476
Price: 76 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1476Cas No. 17184-21-3

Alias Leontoside A

Cauloside A is a bioactive triterpenoid saponin derived from Cimicifuga thalictroides with multifunctional anti-inflammatory, antimicrobial, cytotoxic, hemolytic, and molluscicidal activities. Cauloside A induces concentration-dependent and time-dependent mitochondriotoxic actions, rapidly increasing the cellular respiration rate followed by a dramatic decline within minutes. Mechanistic studies show Cauloside A disrupts mitochondrial membrane integrity, impairing mitochondrial function and contributing to potent biological effects relevant to therapeutic development.

Cauloside A

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Purity: 99.87%

Catalog No. TN1476Alias Leontoside ACas No. 17184-21-3

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$76	-	In Stock
5 mg	$183	-	In Stock
10 mg	$269	-	In Stock
25 mg	$459	-	In Stock
50 mg	$668	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.87%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Synonyms

Leontoside A

Chemical Properties

Molecular Weight	604.81
Formula	C₃₅H₅₆O₈
Cas No.	17184-21-3
Smiles	C[C@]12[C@@]([C@]3(C)[C@@](CC1)([C@@](CO)(C)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O)CO4)CC3)[H])(CC=C5[C@@]2(C)CC[C@]6(C(O)=O)[C@]5(CC(C)(C)CC6)[H])[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (132.27 mM), Sonication is recommeded.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6534 mL	8.2671 mL	16.5341 mL	82.6706 mL
5 mM	0.3307 mL	1.6534 mL	3.3068 mL	16.5341 mL
10 mM	0.1653 mL	0.8267 mL	1.6534 mL	8.2671 mL
20 mM	0.0827 mL	0.4134 mL	0.8267 mL	4.1335 mL
50 mM	0.0331 mL	0.1653 mL	0.3307 mL	1.6534 mL
100 mM	0.0165 mL	0.0827 mL	0.1653 mL	0.8267 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc