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AGA-(C8R) HNG17, Humanin derivative

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Catalog No. TP1524Cas No. 875910-01-3

This peptide is a potent humanin (HN) derivative. It completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.

AGA-(C8R) HNG17, Humanin derivative

AGA-(C8R) HNG17, Humanin derivative

😃Good
Catalog No. TP1524Cas No. 875910-01-3
This peptide is a potent humanin (HN) derivative. It completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
This peptide is a potent humanin (HN) derivative. It completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.
Chemical Properties
Molecular Weight1736.02
FormulaC78H134N20O24
Cas No.875910-01-3
SmilesC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@@H]1CCCN1)C)=O)=O)C)=O)CO)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(C)C)(=O)N2[C@H](C(O)=O)CCC2
Relative Density.1.41 g/cm3 (Predicted)
Sequence ShortPAGASRLLLLTGEIDLP
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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