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PepW is a potent antimicrobial peptide targeting the capsule of multidrug-resistant Klebsiella pneumoniae, with a minimum inhibitory concentration (MIC) of 2-8 μM. It exerts its bactericidal effect by aggregating and disrupting the structure of capsule polysaccharides. PepW holds promise for research into infectious diseases caused by Gram-negative bacteria, such as pneumonia and sepsis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | PepW is a potent antimicrobial peptide targeting the capsule of multidrug-resistant Klebsiella pneumoniae, with a minimum inhibitory concentration (MIC) of 2-8 μM. It exerts its bactericidal effect by aggregating and disrupting the structure of capsule polysaccharides. PepW holds promise for research into infectious diseases caused by Gram-negative bacteria, such as pneumonia and sepsis. |
| Sequence | Trp-Trp-Trp-Ala-{Dab}-Tyr-Gly-Leu-{Dab}-Leu-Leu-{Dab}-Tyr-{Dab}-{Dab}-Trp-Tyr |
| Sequence Short | WWWA-{Dab}-YGL-{Dab}-LL-{Dab}-Y-{Dab}-{Dab}-WY |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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