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14,15-EE-8(Z)-E

Name: 14,15-EE-8(Z)-E
Brand: TargetMol
SKU: T36151
Rating: 4.5 (1 reviews)

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Catalog No. T36151Cas No. 519038-93-8

Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator agonist activity in bovine coronary arteries similar to that of 14(15)-EET.

14,15-EE-8(Z)-E

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Catalog No. T36151Cas No. 519038-93-8

Pack Size	Price	USA Warehouse	Global Warehouse
25 μg	$173	35 days	35 days
50 μg	$323	35 days	35 days
100 μg	$596	35 days	35 days
500 μg	$2,660	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	324.505
Formula	C₂₀H₃₆O₃
Cas No.	519038-93-8
Smiles	CCCCC[C@@H]1O[C@@H]1CCCC\C=C/CCCCCCC(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 0.5 mg/mL (1.54 mM), Sonication is recommended.

DMSO: 10 mg/mL (30.82 mM), Sonication is recommended.

Ethanol: 10 mg/mL (30.82 mM), Sonication is recommended.

DMF: 10 mg/mL (30.82 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	3.0816 mL	15.4081 mL	30.8162 mL	154.0808 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6163 mL	3.0816 mL	6.1632 mL	30.8162 mL
10 mM	0.3082 mL	1.5408 mL	3.0816 mL	15.4081 mL
20 mM	0.1541 mL	0.7704 mL	1.5408 mL	7.7040 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

14,15-EE-8E14,15EE8(Z)E14,15 EE 8(Z) E